Fully absorbable poly-4-hydroxybutyrate implants exhibit more favorable cell-matrix interactions than polypropylene
نویسندگان
چکیده
منابع مشابه
Characterization of the Mechanical Strength, Resorption Properties, and Histologic Characteristics of a Fully Absorbable Material (Poly-4-hydroxybutyrate—PHASIX Mesh) in a Porcine Model of Hernia Repair
Purpose. Poly-4-hydroxybutyrate (P4HB) is a naturally derived, absorbable polymer. P4HB has been manufactured into PHASIX Mesh and P4HB Plug designs for soft tissue repair. The objective of this study was to evaluate mechanical strength, resorption properties, and histologic characteristics in a porcine model. Methods. Bilateral defects were created in the abdominal wall of n = 20 Yucatan minip...
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A series of amphiphilic alternative block polyurethane copolymers based on poly(3-hydroxybutyrate-co-4-hydroxybutyrate) (P3/4HB) and poly(ethylene glycol) (PEG) were synthesized by a coupling reaction between P3/4HB-diol and PEG-diisocyanate, with different 3HB, 4HB, PEG compositions and segment lengths. Stannous octanoate was used as catalyst. The chemical structure, alternative block arrangem...
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Based on direct sucrose conversion, the bacterium Burkholderia sacchari is an excellent producer of the microbial homopolyester poly(3-hydroxybutyrate) (PHB). Restrictions of the strain's wild type in metabolizing structurally related 3-hydroxyvalerate (3HV) precursors towards 3HV-containing polyhydroxyalkanoate (PHA) copolyester calls for alternatives. We demonstrate the highly productive bios...
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received: 23/sep/2008, accepted: 23/nov/2008oct-4/ pou5f1/ oct-3, a pou domain family protein acts as a crucial transcription factor dur- ing embryonic development. it helps in maintenance of self renewal as well as pluripotential state of embryonic stem (es) cells. its expression starts right from 2 cell stage especially prior to 8 cell stage till the blastocyst stage where it is strongly exp...
متن کاملIn vitro hemocompatibility evaluation of poly (4-hydroxybutyrate) scaffold.
The biosynthetic thermoplastic poly-4-hydroxybutyrate (P4HB) possesses favorable tensile strength and elongation performance and has been studied as a new implantable polymer material for medical uses. However, its hemocompatibility has not been tested to confirm its applicability to tissue engineering. In this study, a series of experiments was performed that included erythrocyte hemolysis tes...
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ژورنال
عنوان ژورنال: Materials Science and Engineering: C
سال: 2021
ISSN: 0928-4931
DOI: 10.1016/j.msec.2020.111702